This effectiveness study, in the category of CAM health education, is based on the premise that intuition, health and spiritual wellbeing are interrelated; a change in one affects change in the others. Intuition as a poorly understood function of the mind and body has limited empirical research or application in the health domain. As a source for spiritual awareness, intuition continues to have limited recognition as a factor critical to healing. Nursing research identifies intuition as a valid form of knowledge. The purpose of this study is to advance understanding that intuition is a practical and reliable resource for health and is a pathway to spiritual awareness. Because women are twice as likely as men to experience depression, there is, in addition, an emphasis on advancing a transpersonal energetic understanding of depression and other factors specifically impeding womens intuitive receptivity. A significant change occurred in one aspect of self-actualization. Depression scores showed significant improvement in the experimental group in 12 weeks. Over 65% of the women reported more reliable connection with intuition; more than 50% took action on their intuitive insights in the course of their personal lives.